Phosphatase Inhibitor Cocktail I (100? ddH2O)

TargetMol
Product Code: TAR-C0002
Supplier: TargetMol
CodeSizePrice
TAR-C0002-1mL1 mL£94.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-C0002-1mL*101 mL * 10£235.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-C0002-1mL*501 mL * 50£746.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-C0002-1mL*1001 mL * 100£1,063.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Further Information

Bioactivity:
It is easy for the proteins to be degraded or dephosphorylated during in vitro extraction procedure, which could cause an inaccurate result of protein expression detection. Therefore, adding protease inhibitors or phosphatase inhibitors into the extracts would be an effective method to prevent degradation and dephosphorylation of protein. The phosphatase inhibitor mixture can effectively inhibit the dephosphorylation of common phosphatases on proteins and maintain the original phosphorylation state of proteins.
CAS:
C0002

References

Ren Y, Wang A, Wu D, et al. Dual inhibition of innate immunity and apoptosis by human cytomegalovirus protein UL37x1 enables efficient virus replication. Nature Microbiology. 2022: 1-13 Zhang B, Fan M, Fan J, et al. Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization. Microbiology Spectrum. 2022, 10(1): e02265-21. Pei Y, Lv S, Shi Y, et al. RAB21 controls autophagy and cellular energy homeostasis by regulating retromer-mediated recycling of SLC2A1/GLUT1. Autophagy. 2022: 1-17 Tang H, Guo J, Sang B, et al. PDGFR? Modulates Aerobic Glycolysis in Osteosarcoma HOS Cells via the PI3K/AKT/mTOR/c-Myc Pathway. Biochemistry and Cell Biology. 2021 (ja). Wang T, Wang D, Sun Y, et al.Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer.Journal of Experimental & Clinical Cancer Research.2023, 42(1): 297. Chen Q, Han H, Lin F, et al. Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis. Life Sciences. 2022: 121077 Zhang B, Fan M, Fan J, et al. Avian hepatitis E virus ORF2 protein interacts with Rap1b to induce cytoskeleton 1 rearrangement that facilitates virus internalization 2. Microbiology Spectrum. 2022, 10(1): e02265-21 Gao X, You J, Gong Y, et al. WSB1 regulates c-Myc expression through ?-catenin signaling and forms a feedforward circuit. Acta Pharmaceutica Sinica B. 2021 Yin H, Chen X, Chi Q, et al. The hybrid oncolytic peptide NTP-385 potently inhibits adherent cancer cells by targeting the nucleus. Acta Pharmacologica Sinica. 2022: 1-10. Zhang Y, Zhang J, Chen Y, et al. The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I. Proceedings of the National Academy of Sciences. 2021, 118(23). Wang L, Deng K, Gong L, et al. Chlorquinaldol targets the ?-catenin and T-cell factor 4 complex and exerts anti-colorectal cancer activity. Pharmacological Research. 2020: 104955. Zhu C, Zhang L, Zhao S, et al. UPF1 promotes chemoresistance to oxaliplatin through regulation of TOP2A activity and maintenance of stemness in colorectal cancer. Cell death & disease. 2021, 12(6): 1-15. Liu F, Wang X, Duan J, et al. A Temporal PROTAC Cocktail?Mediated Sequential Degradation of AURKA Abrogates Acute Myeloid Leukemia Stem Cells. Advanced Science. 2022: 2104823 Ren Y, Wang A, Zhang B, et al.Human cytomegalovirus UL36 inhibits IRF3-dependent immune signaling to counterbalance its immunoenhancement as apoptotic inhibitor.Science Advances.2023, 9(40): eadi6586. Wang C, Hu R, Wang T, et al.A bivalent ?-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A.Journal of Biological Chemistry.2023: 104605. Liu L, Lei Y, Chen W, et al.In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-?B modulator in lung cancer.Cell & Bioscience.2022, 12(1): 1-21. Li B, Yang T, Liu J, et al.Genetically engineered PD-1 displaying nanovesicles for synergistic checkpoint blockades and chemo-metabolic therapy against non-small cell lung cancer.Acta Biomaterialia.2023, 161: 184-200. Tabasum S, Thapa D, Giobbie-Hurder A, et al.EDIL3 as an angiogenic target of immune exclusion following checkpoint blockade.Cancer Immunology Research.2023 Li W, Liang J, Li S, et al.The CXCL12-CXCR4-NLRP3 axis promotes Schwann cell pyroptosis and sciatic nerve demyelination in rats.Clinical and Experimental Immunology.2023: uxad081. Yin H, Fu X Y, Gao H Y, et al.Design, synthesis and anticancer evaluation of novel oncolytic peptide-chlorambucil conjugates.Bioorganic Chemistry.2023: 106674. Li J, Dang P, Li Z, et al.Peroxisomal ERK mediates Akh/glucagon action and glycemic control.Cell Reports.2023, 42(10). Lin H, Ai D, Liu Q, et al.Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.Journal of Natural Products.2023 Wang C, Wang T, Hu R, et al.9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3? and HSP90?.Journal of Virology.2023: e01984-22. Wu K, Zhang Y, Liu Y, et al.Phosphorylation of UHRF2 affects malignant phenotypes of HCC and HBV replication by blocking DHX9 ubiquitylation.Cell Death Discovery.2023, 9(1): 27. Pirri C, Caroccia B, Angelini A, et al.A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP).International Journal of Molecular Sciences.2023, 24(20): 15389.