Phosphatase Inhibitor Cocktail III (2 Tubes, 100x)

TargetMol
Product Code: TAR-C0004
Supplier: TargetMol
CodeSizePrice
TAR-C0004-2mL2 mL£105.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-C0004-20mL20 mL£328.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-C0004-100mL100 mL£1,085.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-C0004-200mL200 mL£1,559.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Further Information

Bioactivity:
It is easy for the proteins to be degraded or dephosphorylated during in vitro extraction procedure, which could cause an inaccurate result of protein expression detection. Therefore, adding protease inhibitors or phosphatase inhibitors into the extracts would be an effective method to prevent degradation and dephosphorylation of protein. The phosphatase inhibitor mixture can effectively inhibit the dephosphorylation of common phosphatases on proteins and maintain the original phosphorylation state of proteins.
CAS:
C0004

References

Li H, Liu N N, Li J R, et al. Bicyclol ameliorates advanced liver diseases in murine models via inhibiting the IL-6/STAT3 signaling pathway. Biomedicine & Pharmacotherapy. 2022, 150: 113083 Song X, Qiao L, Chang J, et al. Dietary supplementation with selenium nanoparticles-enriched Lactobacillus casei ATCC 393 alleviates intestinal barrier dysfunction of mice exposed to deoxynivalenol by regulating endoplasmic reticulum stress and gut microbiota. Ecotoxicology and Environmental Safety. 2022, 248: 114276. Li H, Liu N N, Li J R, et al. Combined Use of Bicyclol and Berberine Alleviates Mouse Nonalcoholic Fatty Liver Disease. Frontiers in pharmacology. 2022, 13: 843872-843872. Li H, Liu N N, Li J R, et al. Combined Use of Bicyclol and Berberine Alleviates Mouse Nonalcoholic Fatty Liver Disease. Frontiers in pharmacology. 2022, 13: 843872-843872. Jin C, Ou Q, Chen J, et al. Chaperone-mediated autophagy plays an?important role in?regulating retinal progenitor cell homeostasis. Stem Cell Research & Therapy. 2022, 13(1): 1-14 Guo D, Yang X, Gao M, et al. Deficiency of Autism-Related Gene Dock4 Leads to Impaired Spatial Memory and Hippocampal Function in Mice at Late Middle Age. Cellular and Molecular Neurobiology. 2022: 1-18 Qian H, Zhou T, Fu Y, et al. Self-assembled Tetrahedral Framework Nucleic Acid Mediated Tumor-associated Macrophages Reprogramming and Restores Antitumor Immunity. Molecular Therapy-Nucleic Acids. 2022 Xiong T C, Wei M C, Li F X, et al. The E3 ubiquitin ligase ARIH1 promotes antiviral immunity and autoimmunity by inducing mono-ISGylation and oligomerization of cGAS. Nature Communications. 2022, 13(1): 1-19. Yang H, Ting X, Geng Y H, et al. The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression. Science Advances. 2022, 8(23): eabn3509 Su J, Thakur A, Pan G, et al.Morus alba derived Kuwanon: A combined with 5?fluorouracil reduce tumor progression via synergistic activation of GADD153 in gastric cancer.MedComm?Oncology.2023, 2(1): e24. Liang J, Zhao G, Bian Y, et al.HNF4G increases cisplatin resistance in lung adenocarcinoma via the MAPK6/Akt pathway.PeerJ.2023, 11: e14996. Zhong L, Ren X, Ai Y, et al. SS-31 Improves Cognitive Function in Sepsis-Associated Encephalopathy by Inhibiting the Drp1-NLRP3 Inflammasome Activation. NeuroMolecular Medicine. 2022: 1-12. Wang F, Qi Q, Qin B, et al.Targeting VCP potentiates immune checkpoint therapy for colorectal cancer.Cell Reports.2023, 42(11). Hu H, Xu L, Luo S J, et al. Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma. International Journal of Medical Sciences. 2020, 17(13): 1897 Shi Y, Cui X, Jiang T, et al. The therapeutic effect of KSP inhibitors in preclinical models of cholangiocarcinoma. Cell Death & Disease. 2022, 13(9): 1-13. Tang H, Guo J, Sang B, et al. PDGFR? Modulates Aerobic Glycolysis in Osteosarcoma HOS Cells via the PI3K/AKT/mTOR/c-Myc Pathway. Biochemistry and Cell Biology. 2021 (ja). Jin J, Ou Q, Wang Z, et al. BMSC-derived extracellular vesicles intervened the pathogenic changes of scleroderma in mice through miRNAs. Stem cell research & therapy. 2021, 12(1): 1-16. Li L, Xu X, Lv K, et al. Asebogenin Suppresses Thrombus Formation via Inhibition of Syk Phosphorylation. British Journal of Pharmacology. 2022 Zhang F, Hu G, Chen X, et al. Excessive branched-chain amino acid accumulation restricts mesenchymal stem cell-based therapy efficacy in myocardial infarction. Signal Transduction and Targeted Therapy. 2022, 7(1): 1-18 Du T, Zhang Z, Zhou J, et al. A Novel PARP Inhibitor YHP-836 For the Treatment of BRCA-Deficiency Cancers. Frontiers in pharmacology. 2022, 13. Zhang Y, Wu K, Liu Y, et al.UHRF2 promotes the malignancy of hepatocellular carcinoma by PARP1 mediated autophagy.Cellular Signalling.2023: 110782. Zeng Z, Li T, Liu X, et al.DNA dioxygenases TET2 deficiency promotes cigarette smoke induced chronic obstructive pulmonary disease by inducing ferroptosis of lung epithelial cell.Redox Biology.2023: 102916. Meng Q, Wu W, Zhang W, et al.IL-18BP Improves Early Graft Function and Survival in Lewis?Brown Norway Rat Orthotopic Liver Transplantation Model.Biomolecules.2022, 12(12): 1801. Hu H, Luo S J, Cao Z, et al. Depressive Disorder promotes Hepatocellular Carcinoma metastasis via upregulation of ABCG2 gene expression and maintenance of self-renewal. Journal of Cancer. 2020, 11(18): 5309-5317 Liu H, Mi Q, Ding X, et al. Discovery and characterization of novel potent BCR-ABL degraders by conjugating allosteric inhibitor. European Journal of Medicinal Chemistry. 2022: 114810 Li G N, Zhao X J, Wang Z, et al. Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation. Signal Transduction and Targeted Therapy. 2022, 7(1): 1-15. Niu Z, Wang L, Qin X, et al. Macrophage derived miR-7219-3p-containing exosomes mediate fibroblast trans-differentiation by targeting SPRY1 in silicosis. Toxicology. 2022: 153310. Lu B, Zhu Z, Sheng L, et al. SMARCB1 Promotes Ubiquitination and Degradation of NR4A3 via Direct Interaction Driven by ROS in Vascular Endothelial Cell Injury. Oxidative medicine and cellular longevity. 2020 Oct 23;2020:2048210 Wu F, Xie X, Li G, et al. AKG induces cell apoptosis by inducing reactive oxygen species?mediated endoplasmic reticulum stress and by suppressing PI3K/AKT/mTOR?mediated autophagy in renal cell carcinoma. Environmental Toxicology. 2022 Hu S, Wang Z, Jin C, et al. Human amniotic epithelial cell-derived extracellular vesicles provide an extracellular matrix-based microenvironment for corneal injury repair. Journal of Tissue Engineering. 2022, 13: 20417314221122123 Shi S, Gu H, Xu J, et al.Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity.Experimental & Molecular Medicine.2023: 1-12. Jiao J, Ruan L, Cheng C, et al.Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-?B/JNK/ERK phosphorylation.Molecular Medicine.2023, 29(1): 1-17. Xue D D, Wei C L, Zhou Y H, et al. TRIOL Inhibits Rapid Intracellular Acidification and Cerebral Ischemic Injury: The Role of Glutamate in Neuronal Metabolic Reprogramming. ACS Chemical Neuroscience. 2022