anti-CAIX (CA9) Rabbit Monoclonal (RM486)
| Code | Size | Price |
|---|
| REV-31-1378-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM486
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
BLUE ICE
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Carbonic Anhydrase IX; CA9, Renal Cell Carcinoma-associated Antigen G250; RCC-associated Antigen G250; P54/58N
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the C-terminus of human CAIX (CA9) (Carbonic Anhydrase 9).
Long Description:
Recombinant Antibody. This antibody reacts to human CAIX (CA9) (Carbonic Anhydrase 9). Source: Rabbit. Isotype: Rabbit IgG. Immunogen: A peptide corresponding to the C-terminus of human CAIX (CA9) (Carbonic Anhydrase 9). Applications: IHC, WB. Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CAIX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CAIX results in increased cell death under hypoxia. Therefore, CAIX has become a reliable histochemical marker of hypoxia.
NCBI, Uniprot Number:
Q16790
Package Type:
Vial
Product Description:
Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CAIX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CAIX results in increased cell death under hypoxia. Therefore, CAIX has become a reliable histochemical marker of hypoxia.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human CAIX (CA9) (Carbonic Anhydrase 9).
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.