Coumarin-3-carboxylic acid
| Code | Size | Price |
|---|
| CDX-C0357-G025 | 25 g | £126.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short term: +20°C. Long term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
3-CCA; 3-Carboxycoumarin; 2-Oxo-2H-1-benzopyran-3-carboxylic acid; BRN 0154276; NSC 14797; NSC 53239
Appearance:
Beige powder.
CAS:
531-81-7
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS06
Handling Advice:
Protect from light and moisture.
Hazards:
H301
InChi:
InChI=1S/C10H6O4/c11-9(12)7-5-6-3-1-2-4-8(6)14-10(7)13/h1-5H,(H,11,12)
InChiKey:
ACMLKANOGIVEPB-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 531-81-7. Formula: C10H6O4. MW: 190.15. Coumarin-3-carboxylic acid can be used for quantitative, sensitive, specific detection of hydroxyl radicals (.OH) in aqueous solutions. Spectral Data: lambdaex=395nm; lambdaem=450nm. Fluorescence detection of 3-CCA hydroxylation allows real-time measurement of the kinetics of .OH generation (by gamma-irradiation or chemically). Coumarin-3-carboxylic acid is also a building block and intermediate for the synthesis of coumarins which are well known natural products for their diverse biological activities.
MDL:
MFCD00006852
Molecular Formula:
C10H6O4
Molecular Weight:
190.15
Package Type:
Vial
PG:
III
Precautions:
P301 + P310
Product Description:
Coumarin-3-carboxylic acid can be used for quantitative, sensitive, specific detection of hydroxyl radicals (.OH) in aqueous solutions. Spectral Data: lambdaex=395nm; lambdaem=450nm. Fluorescence detection of 3-CCA hydroxylation allows real-time measurement of the kinetics of .OH generation (by gamma-irradiation or chemically). Coumarin-3-carboxylic acid is also a building block and intermediate for the synthesis of coumarins which are well known natural products for their diverse biological activities.
Purity:
>98% (NMR)
Signal Word:
Danger
SMILES:
O=C1OC2=CC=CC=C2C=C1C(O)=O
Solubility Chemicals:
Soluble in DMSO. Slightly soluble in water (1mg/ml).
Transportation:
Excepted Quantity
UN Nummer:
UN2811
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
12171500
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
[1] Y. Manevich, et al.; Radiat. Res. 148, 580 (1997) | [2] B. Thati, et al.; Cancer Lett. 248, 321 (2007) | [3] S. Yamashita, et al.; Free Radic. Res. 46, 861 (2012) | [4] H. Ji, et al.; Bioorg. Med. Chem. 29, 115870 (2021) | [5] S.N. Esfahani, et al.; Sci. Rep. 11, 20088 (2021) | [6] Q.Yang, et al.; Photochem. Photobiol. Sci. 21, 1481 (2022)