ANGPTL3 (mouse/rat) Dual ELISA Kit
| Code | Size | Price |
|---|
| AG-45A-0015YEK-KI01 | 96 wells | £570.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
BLUE ICE
Storage:
Short term: +4°C. Long term: +4°C
Further Information
Alternate Names/Synonyms:
Angiopoietin-like Protein 3; Angiopoietin-5; ANG-5
Assay Type:
Sandwich
Detection Type:
Colorimetric
EClass:
32160000
Handling Advice:
After standard reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Plate and reagents should reach room temperature before use.
Long Description:
ELISA Assay. Detects mouse and rat ANGPTL3. Does not cross-react with human ANGPTL3, mouse ANGPTL4 or human ANGPTL4. Colorimetric assay. Sample Types: Cell Culture Supernatant, Plasma, Serum. Range: 0.016 to 1ng/ml. Sensitivity: 15pg/ml. Seven proteins containing an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain, both characteristics of angiopoietins, have been identified and therefore designated angiopoietin-like proteins 1-7 (ANGPTL 1-7). ANGPTL3 and ANGPTL6 (Angiopoietin-related growth factor; AGF), among others, function to regulate angiogenesis and also appear to directly regulate lipid, glucose, and energy metabolism. ANGPTL3 plasma levels are increased in a mouse model of diabetes mellitus.
NCBI, Uniprot Number:
Q9R182
Package Type:
Box
Product Description:
Seven proteins containing an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain, both characteristics of angiopoietins, have been identified and therefore designated angiopoietin-like proteins 1-7 (ANGPTL 1-7). ANGPTL3 and ANGPTL6 (Angiopoietin-related growth factor; AGF), among others, function to regulate angiogenesis and also appear to directly regulate lipid, glucose, and energy metabolism. ANGPTL3 plasma levels are increased in a mouse model of diabetes mellitus.
Range:
0.016 to 1ng/ml
Sample Type:
Cell Culture Supernatant, Plasma, Serum
Sensitivity:
15pg/ml
Specificity:
Detects mouse and rat ANGPTL3. Does not cross-react with human ANGPTL3, mouse ANGPTL4 or human ANGPTL4.
Transportation:
Non-hazardous
UNSPSC Category:
ELISA Kits
UNSPSC Number:
41116126
Use & Stability:
12 months after the day of manufacturing. See expiry date on ELISA Kit box.
References
Atypical angiopoietin-like protein that regulates ANGPTL3: F. Quagliarini, et al.; PNAS 109, 19751 (2012) | Hepatic ANGPTL3 regulates adipose tissue energy homeostasis: Y. Wang, et al.; PNAS 112, 11630 (2015) | A vital role for Angptl3 in the PAN-induced podocyte loss by affecting detachment and apoptosis in vitro: R. Dai, et al.; BMC Nephrol. 16, 38 (2015)