KRISHZYME™ Enoxaparin Factor IIa Assay Kit
| Code | Size | Price |
|---|
| KBBA03ES | 100 tests / 1 kit | £546.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
2-8 ℃C
Further Information
Calibration Range:
0.010IU/ml - 0.040 IU/ml
Detection Method:
Colorimetric, 450nm
Product Description:
Chromogenic assay for testing Enoxaparin in purified systems by measurement of
factor IIa inhibition, in compliance with pharmacopoeias (EP/BP) and FDA guidelines
About the kit:
- Uses anti-idiotypic antibodies sourced from our vendor partner in the US, which ensures higher specificity, and low cross reactivity.
- Recovery rates are between 85 - 115%
- Ready to use with a standard protocol with break-apart pre-coated wells
- Validated as per US FDA guidelines for Bioassays
- Optimized for matrix effects to ensure higher sensitivity.
- Shelf life: 1 year
The inhibitory effect of anti-thrombin III (AT-III) on thrombin, factor IIa and other coagulation serine proteases in
plasma is increased several thousand-fold by enoxaparin. This inhibition accounts for the anticoagulant effect of
enoxaparin. The quantitative determination of enoxaparin levels by the measurement of their anti-IIa activity is a
necessary tool for monitoring treatment efficacy.
Presence of Enoxaparin catalyzes the reaction between AT lll and ?-Thrombin. The factor IIa inhibition test is the
most useful assay covering the widest variety of enoxaparin preparations. In the assay, the rate of factor IIa
inhibition is directly proportional to the enoxaparin concentration since both factor IIa and AT-III are in excess. The
residual factor IIa activity is inversely proportional to the enoxaparin concentration.
Sample Type:
Cell Culture Supernatant and Pharmaceutical Preparations
Sensitivity:
Please refer to the current IFU for the updated calibrator range and sensitivity.