Irisin (rec.) (HEK293)

Fibronectin Type III Domain-containing Protein 5 (cleaved); Fibronectin Type III Repeat-containing Protein 2 (cleaved); FNDC5 (cleaved)

0.1mg/ml after reconstitution.

32160000

<0.1EU/ug purified protein (LAL test; Lonza).

solid

Lyophilized. Contains PBS.

After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0. 1% BSA should be used for further dilutions.

Recombinant protein. Irisin (human, aa 32-143 /mouse, aa 29-140) is FLAG ®-tagged at the N-terminus. Irisin has 100% identity between mouse, rat, monkey and human. Source: HEK 293 cells. Lyophilized. Contains PBS. Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.

~26kDa

Q8NAU1

Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.

>95% (SDS-PAGE)

Irisin (human, aa 32-143 /mouse, aa 29-140) is FLAG ®-tagged at the N-terminus. Irisin has 100% identity between mouse, rat, monkey and human.

HEK 293 cells

FLAG

Non-hazardous

12352202

Stable for at least 6 months after receipt when stored at -20°C.