anti-cGMP, Rabbit Monoclonal (RM467)

RevMab Biosciences
Product Code: REV-31-1359-00
Product Group: Primary Antibodies
CodeSizePrice
REV-31-1359-00-C05050 ug£484.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM467
Regulatory Status: RUO
Target Species: Species Independent
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
BLUE ICE
Storage:
Long term storage:-20°C.

Images

1 / 1
Competitive ELISA showing the specificity of anti-cGMP (RM467). The 96-well plate was coated with 1 ug/mL of Goat anti-rabbit IgG (50 ?l/well). 0.05 ?g/ml of anti-cGMP (RM467)(50 ?l/well) was added and incubated. After wash and block, cGMP and other cyclic nucleotides or nucleoside phosphates (25 ?l/well) were added along with 25 ?l/well of 1/5,000 diluted HRP conjugated cGMP. TMB was used to develop the color after incubation and wash.

Competitive ELISA showing the specificity of anti-cGMP (RM467). The 96-well plate was coated with 1 ug/mL of Goat anti-rabbit IgG (50 ?l/well). 0.05 ?g/ml of anti-cGMP (RM467)(50 ?l/well) was added and incubated. After wash and block, cGMP and other cyclic nucleotides or nucleoside phosphates (25 ?l/well) were added along with 25 ?l/well of 1/5,000 diluted HRP conjugated cGMP. TMB was used to develop the color after incubation and wash.

Documents

Further Information

Alternate Names/Synonyms:
Cyclic Guanosine Monophosphate
Concentration:
1 mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
KLH-conjugated cGMP.
Long Description:
Recombinant Antibody. RM467 reacts to cGMP (Cyclic Guanosine Monophosphate). No cross-reactivity with other cyclic nucleotide or nucleoside phosphate. Isotype: Rabbit IgG. Immunogen: KLH-conjugated cGMP. Applications: ELISA. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
Package Type:
Vial
Product Description:
Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
RM467 reacts to cGMP (Cyclic Guanosine Monophosphate). No cross-reactivity with other cyclic nucleotide or nucleoside phosphate.
Transportation:
Non-hazardous
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.