Anti-Human CD2 - Purified
| Code | Size | Price |
|---|
| LEI-C109-50ug | 50 ug | £126.00 |
Quantity:
| LEI-C109-100ug | 100 ug | £152.00 |
Quantity:
| LEI-C109-200ug | 200 ug | £197.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: G11
Regulatory Status: RUO
Target Species: Human
Applications:
- Co-stimulation
- Flow Cytometry
Shipping:
Ambient
Storage:
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Further Information
Antigen Distribution:
CD2 is present on normal peripheral blood lymphocytes, thymocytes, mature circulating T-cells and a subset of NK cells.
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified
Format:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Long Description:
CD2 is a 45-59 kD type I transmembrane glycoprotein belonging to the Ig superfamily. CD2 is the receptor for LFA-3/CD58. CD2 serves as an adhesion receptor that binds to CD58; generating the activation of CD2-positive T cells and NK cells and in the regulation of their cytolytic activities. CD2 is a specific marker for T cells and NK cells. Hence, it can be used in immunohistochemistry to identify the occurrence of these cells in tissue sections. The vast majority of T cell lymphomas and leukemias express CD2 which makes it possible to distinguish these conditions from B-cell lymphomas.
NCBI Gene:
914
Target:
CD2
References
1. Stern, LJ. et al. (2005) Proc Natl Acad Sci U S A.102(10):3744-9 PubMed
2. Meuer, S.C. et al. (1984) Cell 36:897
3. Peterson, A. and Sneed, B. (1987) Nature 329:842
4. Bierer, B.E. et al. (1989) Annu. Rev Immunol. 7:579
5. Krensky, C.F. et al. (1982) Proc. Natl. Acad. Sci. USA 79:7489
6. Krensky, C.F. et al. (1983) J. Immunol. 131:611