Anti-Human CD14 - Biotin
| Code | Size | Price |
|---|
| LEI-C154-50ug | 50 ug | £152.00 |
Quantity:
| LEI-C154-100ug | 100 ug | £209.00 |
Quantity:
| LEI-C154-200ug | 200 ug | £303.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: UCHM-1
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
Ambient
Storage:
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Further Information
Antigen Distribution:
CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes.
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Biotin
Format:
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Long Description:
CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.
NCBI Gene:
929
Target:
CD14
References
1. Freyssinet, JM et al. (1997) J Clin Invest. 99(7): 1546?1554. PubMed
2. Ulrich, Costabel et al. (1995) CHEST 108: 1614
3. Ulevitch, RJ et al. (1993) Immunobiology 187: 227
4. Schumann, RR et al. (1994) Medical Microbiol Immunol. 183: 279
5. Verhasselt, V et al. (1997) J Immunol. 158: 2919
6. Kirkland, TN et al. (2000) J Biol Chem. 275: 3144
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