Anti-Human CD62E (E-Selectin) - Purified
Code | Size | Price |
---|
LEI-C674-0.1mg | 0.1 mg | £625.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 1.2B6
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
Ambient
Storage:
For use within 1 month of purchase store at 2-8°C. For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Further Information
Concentration:
0.1 mg/ml
Conjugate/Tag/Label:
Purified
Format:
This purified monoclonal antibody is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Formulation:
This purified monoclonal antibody is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Immunogen:
TNF-Activated Human Umbilical Vein Endothelial Cells
Long Description:
E-selectin, also known as CD62E is an inducible leukocyte adhesion glycoprotein specifically expressed by endothelial cells.1 E-selectin helps initiate recruitment of circulating leukocytes to cutaneous, bone and inflamed tissues.2 E-selectin is found in inflammatory skin lesions in psoriasis, contact dermatitis, and delayed- type hypersensitivity, in arthritic joints, and in heart and renal allografts undergoing rejection.3 E-selectin-targeting antibody drug conjugate has potential as a prostate cancer therapy.4
NCBI Gene:
6401
Target:
CD62E
References
1. Milstone D et al. (2004) PNAS 101: 8005
2. Dimitroff CJ et al. (2009) J Visualized Experiments
3. Takako Hirata et al. (2005) J Immunol. 175: 8042
4. Ramakrishnan Vanitha et al. (2003) Cancer Res. 63: 6387