Anti-Human CD62E (E-Selectin) - FITC
| Code | Size | Price |
|---|
| LEI-C675-100tests | 100 tests | £586.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 1.2B6
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
Ambient
Storage:
Store at 2-8°C protected from light. DO NOT FREEZE. For long term storage aliquot conjugate into working volumes and store at 2-8°C for up to a year.
Further Information
Conjugate/Tag/Label:
Fluorescein (FITC)
Format:
This conjugate is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Formulation:
This conjugate is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Immunogen:
TNF-Activated Human Umbilical Vein Endothelial Cells
Long Description:
E-selectin, also known as CD62E is an inducible leukocyte adhesion glycoprotein specifically expressed by endothelial cells.1 E-selectin helps initiate recruitment of circulating leukocytes to cutaneous, bone and inflamed tissues.2 E-selectin is found in inflammatory skin lesions in psoriasis, contact dermatitis, and delayed- type hypersensitivity, in arthritic joints, and in heart and renal allografts undergoing rejection.3 E-selectin-targeting antibody drug conjugate has potential as a prostate cancer therapy.4
NCBI Gene:
6401
Target:
CD62E
References
1. Milstone D et al. (2004) PNAS 101: 8005
2. Dimitroff CJ et al. (2009) J Visualized Experiments
3. Takako Hirata et al. (2005) J Immunol. 175: 8042
4. Ramakrishnan Vanitha et al. (2003) Cancer Res. 63: 6387