Anti-Mouse CD28 - Purified
| Code | Size | Price |
|---|
| LEI-C243-50ug | 50 ug | £130.00 |
Quantity:
| LEI-C243-500ug | 500 ug | £254.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: 37.51
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Blocking
- Co-stimulation
- Flow Cytometry
- Immunohistochemistry- Frozen Section (IHC-F)
- Immunoprecipitation (IP)
Shipping:
Ambient
Storage:
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Further Information
Antigen Distribution:
CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified
Format:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Long Description:
CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
NCBI Gene:
12487
Target:
CD28
References
Gross, J. A. et al. (1992) J. Immunol. 149:380
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