Anti-Mouse Ly-6C (Clone HK1.4) - Purified in vivo GOLD™ Functional Grade

Leinco Technologies
Product Code: LEI-L136
Product Group: Primary Antibodies
CodeSizePrice
LEI-L136-1.0mg1.0 mg£175.00
Quantity:
LEI-L136-5.0mg5.0 mg£380.00
Quantity:
LEI-L136-25mg25 mg£1,014.00
Quantity:
LEI-L136-50mg50 mg£1,556.00
Quantity:
LEI-L136-100mg100 mg£2,159.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: IgG2c
Antibody Clonality: Monoclonal
Antibody Clone: HK1.4
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunoprecipitation (IP)
  • In Vivo Assay
  • Mass Cytometry (CyTOF)
  • Spatial Biology
  • Western Blot (WB)
Shipping:
2-8°C
Storage:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Further Information

Antigen Distribution:
The antigen is found on some monocyte/macrophage populations, endothelial cells, thymocytes, NK-cells, T-cell subsets and 40% of bone marrow cells from all mouse strains tested. Clone HK1.4 does not block the binding of clone RB6-8C5
Concentration:
? 5.0 mg/ml
Conjugate/Tag/Label:
in vivo GOLD™, Purified in vivo Functional Grade
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
L3 cloned CTL cells
Long Description:
Most hematopoietic cells express one or more members of Ly-6 family. The expression of Ly-6 varies with development stage and activation. Ly-6C is a 14-17 kD GPI-linked surface protein expressed on mouse monocyte/macrophage cells, endothelial cells, neutrophils, and some T cell subsets. Ly-6C is reported to be an indicator of memory CD8+ T cells.
NCBI Gene:
17067
Purity:
?95% monomer by analytical SEC, >95% by SDS Page
Target:
Ly-6C

References

1.) Havran, W. L. et al. (1988) J. Immunol. 140(4):1034 2.) Gubin, M. et al. (2018) Cell. 175(4):1014?1030.e19 Journal Link

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