Recombinant Mouse Gas6
| Code | Size | Price |
|---|
| LEI-G655-25ug | 25 ug | £716.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Long Description:
Growth arrest-specific 6, also known as GAS6 is a growth factor1 that serves as a ligand for members of the Axl subfamily of receptor protein-tyrosine kinases.2 GAS6 is expressed in hematopoietic tissue.3 GAS6 function as a direct regulator of osteoclastic function; they give an insight into the role of these vitamin K-dependent ligands in bone resorption in vivo.2 GAS6 has a potential therapeutic target to minimize graft-versus-host disease (GVHD).4
NCBI Gene:
14456
Purity:
>95% by SDS-PAGE and analyzed by silver stain.
Target:
Gas6
References
1. Suda, T. et al. (1998) Stem Cells 16: 229
2. Schneider, C. et al. (2001) Mol Cell Biol. 21: 902
3. Aglietta, M. et al. (1997) Exp Hematol. 25: 1219
4. Angelillo-Scherrer, A. et al. (2005) J Clin Invest. 115(2):237-46.
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