Anti-Human Caspase-8 Active Subunit (p18)
| Code | Size | Price |
|---|
| LEI-C1142-0.2mg | 0.2 mg | £313.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2b
Antibody Clonality: Monoclonal
Antibody Clone: C81.349
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
2-8°C
Storage:
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Further Information
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified
Format:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Long Description:
Caspase-8 is a member of the caspase family of cysteine proteases and plays a key role in mediating Fas (CD95) and tumor necrosis factor?1 (TNFR-1) induced apoptosis. Activation of caspase 8 by proteolytic cleavage leads to the release of the active p18 and p10 subunits. These processed subunits associate to form an active enzyme.
Target:
Caspase-8 Active Subunit (p18)
References
1. Muzio, M. et al. (1996) Cell 85: 817 2. Boldin, MP. et al. (1996) Cell 85: 803 3. Fernandes-Alnemri, T. et al. (1996) Proc. Natl. Acad. Sci. USA 93:7464