IL-21R (Extracellular Domain) Blocking Peptide
| Code | Size | Price |
|---|
| LEI-I-355-50ug | 50 ug | £216.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Further Information
Concentration:
0.2 mg/ml
Format:
This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Formulation:
This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Long Description:
Interleukin 21 receptor (IL-21R) is a novel member of the class-I-cytokine-receptor family and is selectively expressed in lymphoid tissues. IL21R shows strong sequence homologies to the interleukin-4 receptor alpha chain gene (IL4RA).1 IL-21R is an important amplifier of alternative macrophage activation. Collectively, these results illustrate an essential function for the IL-21R in the development of pathogen-induced Th2 responses, which may have relevance in therapies for both inflammatory and chronic fibrotic diseases.2 IL-21/IL-21R system may represent a new target for the treatment of Adult T-cell leukaemia (ATL).3
Target:
Interleukin-21 Receptor
References
1. Hackstein H et al. (2003) Genes Immun. 4: 228
2. Wynn TA et al. (2006) J Clin Invest. 116: 2044
3. Uchiyama T et al. (2005) Br J Haematol. 128: 169
Related Products
| Product Name | Product Code | Supplier | Anti-Human IL-21R (Extracellular Domain) | LEI-I-354 | Leinco Technologies | Summary Details | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Anti-Human IL-21R (NT) | LEI-I-356 | Leinco Technologies | Summary Details | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IL-21R (NT) Blocking Peptide | LEI-I-357 | Leinco Technologies | Summary Details | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||