Recombinant Human IL-19
| Code | Size | Price |
|---|
| LEI-I-337-25ug | 25 ug | £580.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Interleukin-19 (IL-19) is a secreted protein that belongs to the IL-10 family of cytokines along with several other interleukins including IL-10, IL-20, IL-22, IL-24, IL-26, and several virus-encoded cytokines. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-19 is expressed in resting monocytes and B cells and is up-regulated in monocytes following stimulation with granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide.1 In addition, IL-19 may play important roles in inflammatory responses due to its ability to upregulate IL-6 and TNF-alpha as well as induce apoptosis.2 Human and murine IL-19 share 71% amino acid sequence identity.
NCBI Gene:
29949
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
IL-19
References
1. Chang, C. et al. (2003) J. of Biol. Chem. 278:3308 2. Chang, MS. et al. (2002) J. Immunol. 169:4288
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