Recombinant Human Oncostatin M
Code | Size | Price |
---|
LEI-O101-10ug | 10 ug | £398.00 |
Quantity:
LEI-O101-50ug | 50 ug | £1,308.00 |
Quantity:
LEI-O101-1mg | 1 mg | £7,999.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Format:
This recombinant protein was lyophilized from a 0.2 um filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Formulation:
This recombinant protein was lyophilized from a 0.2 um filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Long Description:
Oncostatin M (OSM) is a pleitropic cytokine produced by activated T lymphocytes and monocytes that is structurally and functionally related to the subfamily of cytokines known as the IL-6-type cytokine family.1 OSM either inhibits or enhances the growth of cells depending on cell type. It inhibits proliferation of skeletal muscle cells by blocking cell cycle progression from G(1) to S phase.2 OSM is also a key mediator for proliferation and anti-apoptosis of hepatocytes which suggests that OSM gene therapy is useful, as preventive and curative means, for the treatment of patients with liver damage.3
NCBI Gene:
5008
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
OSM
References
1. G?mez-Lech?n, MJ. et al. (1999) Life Sci. 65: 20192. Jo, SA. et al. (2008) Cell Signal 20: 1203. Tsujimura, T. et al. (2007) Am J Pathol. 171: 872
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Anti-Mouse OSM - Biotin | LEI-O133 | Leinco Technologies | Summary Details | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||