Recombinant Human Pleiotrophin
| Code | Size | Price |
|---|
| LEI-P119-50ug | 50 ug | £546.00 |
Quantity:
| LEI-P119-250ug | 250 ug | £1,388.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1), also known as PTN is a growth, differentiation inducing cytokine,1 and neurite extension promoting polypeptide which is highly expressed in brain and in tissues derived from mesenchyme.2 PTN is produced by many different human cancers and stimulates tumor blood vessel formation when it is expressed in malignant cancer cells.3 It is expressed in many types of cancer, such as gliomas, melanomas, meningiomas, neuroblastomas, choriocarcinomas, leukemias and cancers of pancreas, prostate, stomach, colon, breast, ovaries and lungs.4
NCBI Gene:
5764
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
Pleiotrophin
References
1. Lee, RJ. et al. (2005) Biochem Biophys Res Commun. 332: 1146
2. Deuel, TF. et al. (1992) Biochem Biophys Res Commun. 184: 427
3. Berenson, JR. et al. (2009) Blood 113: 1992
4. Papadimitriou, E. et al. (2007) Recent Patents Anticancer Drug Discov. 2: 175
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