Recombinant Rat GDNF Rα1

Product Code: LEI-G648

Code	Size	Price

LEI-G648-100ug

100 ug

£614.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Host Type: Rat

Regulatory Status: RUO

Shipping:

Ambient

Storage:

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Further Information

Format:

This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.

Formulation:

This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.

Long Description:

Glial Cell-Line Derived Neurotrophic Factor Receptor Alpha 1 (GDNFR-alpha 1), also known as GFRA1, is a novel glycosylphosphatidylinositol-linked cell surface receptor for glial cell line-derived neurotrophic factor (GDNF)1 that is expressed by Spermatogonial stem cells (SSCs).2 GDNF has been known for many years to protect and restore dopamine neurons of the substantia nigra (SN) in lesion models of parkinsonism.3

NCBI Gene:

25454

Purity:

>90% by SDS-PAGE and analyzed by silver stain.

Target:

GFR alpha-1

References

1. Fox, GM. et al. (1996) Cell 85: 1113 2. Schlatt, S. et al. (2005) Biol Rep. 73: 1011 3. Burke, RE. et al. (2006) J Neural Transmission 70: 41

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