Recombinant Human TRAIL R2

Product Code: LEI-T218

Code	Size	Price

LEI-T218-100ug

100 ug

£637.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Host Type: Human

Regulatory Status: RUO

Shipping:

Ambient

Storage:

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Further Information

Format:

This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.

Formulation:

This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.

Long Description:

Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.2 TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients.3

NCBI Gene:

8795

Purity:

>95% by SDS-PAGE and analyzed by silver stain.

Target:

sTRAIL R-2

References

1. Yoo, NJ. et al. (2001) Oncogene 20: 3992. Eberle, J. et al. (2005) J Investigative Dermatol. 125: 1010 3. Burtness, BA. et al. (2005) Clin Cancer Research 11(16):5856-62.