Recombinant Human PK2
| Code | Size | Price |
|---|
| LEI-P171-20ug | 20 ug | £532.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Storage:
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Further Information
Long Description:
Prokineticin 2 (PK2) is a cysteine-rich secreted protein1 that is expressed in the testis and in lower levels of the small intestine. PK2 regulates various biological functions including gastrointestinal motility, angiogenesis, circadiam rhythms, and neurogenesis of olfactory bulb.2 It is closely related to EG-VEGF (Prokineticin-1) and binds to two orphan B-protein-coupled receptors termed PK-R1 and PK-R2. PK2 plays roles in both circadian and homeostatic regulation of sleep. PK2 may also be involved in maintaining the awake state in the presence of behavioral challenges.3
Purity:
>98% by SDS Page and HPLC
Target:
Prokineticin-2
References
1. Zhou QY et al. (2002) Nature 417: 405
2. Zhou QY et al. (2007) J Biol Chem. 282: 6917
3. Zhou QY et al. (2007) Sleep 30: 247