Recombinant Human Nanog
| Code | Size | Price |
|---|
| LEI-N140-20ug | 20 ug | £532.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Storage:
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Further Information
Long Description:
Nanog, a homeobox transcription factor1, plays a key role in maintaining stem cell pluripotency by regulating the expression of genes critical to stem cell renewal and differentiation.2 In other words, these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm). Nanog may be useful in the immunohistochemical diagnosis of tumors. It is expressed in germ cells of the fetus and in some germ cell tumors of the gonads3 and central nervous system.4
Purity:
>98% by SDS Page and HPLC
Target:
Nanog
References
1. Sch?ler HR.et al. (2003) Cell 113: 551
2. Pei D. et al. (2005) J Biol. Chem. 280: 1401
3. Rajpert-De Meyts E. et al. (2005) Histopathology 47: 48
4. Ligon KL. et al. (2006) Am J Surg Pathol. 30: 1613
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