Recombinant Human MIA
| Code | Size | Price |
|---|
| LEI-M109-100ug | 100 ug | £580.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Further Information
Format:
This recombinant protein was 0.2 um filtered and lyophilized from a sterile solution in PBS, pH 7.4 with 5% Trehalose.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from a sterile solution in PBS, pH 7.4 with 5% Trehalose.
Long Description:
Melanoma inhibitory activity (MIA), also known as cartilage derived retinoic acid sensitive protein (CD-RAP)1, is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin. MIA is over-expressed in pancreatic cancer and has the potential of promoting the invasiveness of pancreatic cancer cells.2
NCBI Gene:
8190
Purity:
>95% by SDS-PAGE and HPLC
Target:
MIA
References
1. Sandell, LJ. et al. (1996) J Biol Chem. 271: 3311
2. Friess, H. et al. (2005) Cancer Cell Int. 5: 3