Anti-Mouse IL-1 R1, Type 1 - PE
| Code | Size | Price |
|---|
| LEI-I-433-50ug | 50 ug | £179.00 |
Quantity:
| LEI-I-433-500ug | 500 ug | £333.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: JAMA-147
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
2-8°C
Storage:
This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.
Further Information
Antigen Distribution:
T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells, neural cells
Concentration:
0.2 mg/ml
Conjugate/Tag/Label:
R-phycoerythrin (PE)
Format:
This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen:
Extracellular domain of mouse IL-1R1
Long Description:
IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1α and IL-1β exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1α and IL-1β, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
Target:
Interleukin-1 R1