Recombinant Mouse E-Cadherin

Product Code: LEI-C1355

Code	Size	Price

LEI-C1355-50ug

50 ug

£614.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Host Type: Mouse

Regulatory Status: RUO

Shipping:

Ambient

Storage:

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Further Information

Format:

This recombinant protein was 0.2 um filtered and lyophilized from a sterile solution containing 50mM Tris-Citrate, 50 mM NaCl and 2 mM CaCl2, pH 6.5.

Formulation:

This recombinant protein was 0.2 um filtered and lyophilized from a sterile solution containing 50mM Tris-Citrate, 50 mM NaCl and 2 mM CaCl2, pH 6.5.

Long Description:

Cadherin 1, type 1, E-cadherin (epithelial), also known as CDH1 and CD32, is a tumor suppressor gene. 1, 2 The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. E-cadherin-mediated cell-cell adhesion pathway may represent a novel chemotherapeutic target for bladder cancer, prostate cancer, and renal-cell carcinoma. 3

NCBI Gene:

12550

Purity:

>95% by SDS Page and analyzed by silver stain.

Target:

E-Cadherin

References

1. Christofori, G. et al. (1998) Am. J. Hum. Genet. 63: 1588 2. Gumbiner, BM. et al. (2003) J. Cell Biol.161: 1191 3. Isaacs, WB. et al. (1995) World J Urol. 13:364

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