Recombinant Human IGF-I sR
| Code | Size | Price |
|---|
| LEI-I-560-50ug | 50 ug | £671.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Long Description:
Insulin-like Growth Factor 1 (IGF-1) Receptor is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection.1 IGF-1 receptor may be a central regulator of mammalian lifespan2 and when activated, it results in survival and proliferation in mitosis-competent cells, and growth (hypertrophy) in tissues such as skeletal muscle and cardiac muscle. IGF1R is now an attractive anti-cancer treatment target.1
Purity:
>95% by SDS Page and analyzed by silver stain.
Target:
IGF-I R
References
1. Riedemann, J. and Macaulay, VM. et al. (2006) Endocrine-Related Cancer 13(1):S33-43
2. Le Bouc, Y. et al. (2003) Nature. 421(6919):182-7.
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