Recombinant Human NGF R
| Code | Size | Price |
|---|
| LEI-N187-50ug | 50 ug | £614.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Nerve growth factor receptor (NGFR), also known as the low-affinity receptor p75NTR is a transmembrane glycoprotein without intrinsic tyrosine kinase activity, whose expression is not restricted to neural cells. NGFR is reported to act as a tumour suppressor, negatively regulating cell growth and proliferation.1 It is also involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination.2 p75NGFR contributes to delayed neuronal death (DND) after ischemia by an apoptotic mechanism.3
NCBI Gene:
4804
Purity:
>95% by SDS-PAGE and analyzed by silver stain.
Target:
NGF R
References
1. Ashworth, A. et al. (2006) Modern Path. 19: 307
2. Carter, BD. et al. (2004) Prog. Brain Res. 146: 25
3. Itano, T. et al. (2001) Acta Med Okayama 55: 19
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