Recombinant Human IL-18 Rβ
| Code | Size | Price |
|---|
| LEI-I-545-100ug | 100 ug | £614.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Long Description:
Beta chain of interleukin-18 receptor (IL-18Rbeta) is an accessory protein-like molecule that is required for signaling1 IL-18 signals through its specific cell surface receptor IL-18R, which comprises two subunits: IL-18Rα and IL-18Rβ. IL-18Rα alone has a weak affinity for IL-18 binding, while the IL-18Rα/β complex has a high affinity.2 IL-18 Rβ is detected in numerous tissues including lung, spleen, leukocytes and colon.3
NCBI Gene:
8807
Purity:
>90% by SDS Page and analyzed by silver stain.
Target:
IL-18 R beta
References
1. Churakowa, T. et al. (2000) J. Immunol. 165: 4950
2. Ghayur, T. et al. (2003) J. Immunol. 170: 5571
3. Born, TL. et al. (2000) J. Biol. Chem. 273: 29445
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