Recombinant Human IL-3 Rα

Leinco Technologies
Product Code: LEI-I-559
Product Group: Recombinant Proteins
CodeSizePrice
LEI-I-559-25ug25 ug£773.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Further Information

Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Interleukin 3 receptor alpha (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a type I transmembrane protein that is expressed on the large majority of progenitor cells. IL-3R alpha function can be defined by the activity of its ligand interleukin-3. IL-3 is a multipotent cytokine that promotes the development of hemopoietic progenitors into cells of the erythroid, myeloid and lymphoid lineages.1 CD123 may be a promising strategy for the preferential ablation of acute myelogenous leukemia (AML) cells.2
NCBI Gene:
3563
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
IL-3 R alpha

References

1. Garnache-Ottou, F. et al. (2015) Haematologica. 100(2):223-302. Phillips, GL. et al. (2000) Leukemia 14: 1777

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