Recombinant Human Latent TGF-β1
| Code | Size | Price |
|---|
| LEI-T387-5ug | 5 ug | £608.00 |
Quantity:
| LEI-T387-25ug | 25 ug | £1,359.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Dry Ice
Storage:
Working aliquots of this recombinant protein solution are stable for up to twelve months at -20°C to -70°C in a manual defrost freezer. Upon thawing in the presence of a carrier protein this recombinant protein can be stored at 2° - 8°C for one month without detectable loss of activity. For long-term storage aliquot and freeze at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles.
Further Information
Format:
This recombinant protein solution was 0.2 um filtered and formulated in modified Dulbecco?s phosphate buffered saline (1X PBS) and glycerol pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives present.
Formulation:
This recombinant protein solution was 0.2 um filtered and formulated in modified Dulbecco?s phosphate buffered saline (1X PBS) and glycerol pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives present.
Long Description:
Transforming growth factor beta 1 or TGF-β1 is a multifunctional cytokine that regulates the proliferation and differentiation of cells specific to bone like chondrocytes, osteoblasts, osteoclasts including mesenchymal precursor cells.1 It is known to promote the pathogenesis of lung fibrosis and acts as a tumor suppressor in normal cells.2 TGF-beta1 can promote mechanical strength in healing Achilles tendons by regulating collagen synthesis, cross-link formation, and matrix remodeling.3
NCBI Gene:
7040
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
Latent TGF-beta 1
References
1. Guven, M. et al. (2007) Growth Factors 25: 1012. Schneider, J. et al. (2009) J Investing Med. 57(5):655-613. Yu, C. et al. (2009) Biochem Biophys Res Commun. 406(2):204-210