Anti-SARS-CoV Spike (17aa - Intermediate Domain)
Code | Size | Price |
---|
LEI-S542-20ug | 20 ug | £199.00 |
Quantity:
LEI-S542-0.1mg | 0.1 mg | £591.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Virus
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ambient
Storage:
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Images
Further Information
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Formulation:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Immunogen:
Anti-SARS-CoV Spike antibody was raised against a peptide corresponding to 17 amino acids near the center of SARS-CoV Spike glycoprotein. The immunogen is located within amino acids 550-600 of SARS-CoV Spike.
Long Description:
A novel coronavirus has recently been identified as the causative agent of SARS-CoV.1-2 Coronaviruses are a major cause of upper respiratory diseases in humans.3 The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.4
Target:
SARS Spike
References
1. Marra, M. A. et al. (2003) Science 300:1399
2. Rota, P. A. et al. (2003) Science 300:1394
3. Navas-Nartin, S. R. et al. (2004) J. Neurovirol. 10:75
4. Li, W. et al. (2003) Nature 426:450
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