Recombinant Human FGF R1α (IIIb)
| Code | Size | Price |
|---|
| LEI-F1041-50ug | 50 ug | £580.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Fibroblast growth factor receptor-1 alpha (FGFR1-alpha) is an isoform of FGFR1 which is a receptor tyrosine kinase. FGFR1-alpha is expressed in prostate luminal epithelial cells.1 FGFR1alpha signals are posteriorizing factors that control node regression and posterior embryonic development.2FGFR1-alpha is a splice variant of FGFR1 containing the first immunoglobulin-like domain, whereas FGFR1-beta lacks this domain.2 The presence or absence of this N-terminal domain influences the affinity of the receptor towards aFGF and heparin.3 FGFR1-alpha is expressed in prostate luminal epithelial cells, whereas FGFR1-beta is expressed in basal epithelial cells and smooth muscle cells.
Purity:
>95% by SDS-PAGE and analyzed by silver stain.
Target:
FGF R1 alpha (IIIb)
References
1. Moscatelli, D. et al. (2007) Prostate 67: 1152. Deng, CX. et al. (1999) Dev Biol. 208: 293