Recombinant Human CD120b (TNFR2)
| Code | Size | Price |
|---|
| LEI-T408-50ug | 50 ug | £614.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Format:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives.
Long Description:
Tumor necrosis factor receptor II (TNF-RII, TNFRSF1B, p75, CD120b) is a membrane glycoprotein in the TNF receptor superfamily. It is present on most cell types and is considered to play a prominent role in stimulation by TNF-α (1). TNF-RII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells, as well as endothelial cells, cardiac myocytes and prostate cells (2). Soluble TNF-RII neutralizes the biological activities of TNF-α and TNF-β with equal efficiency (3).
NCBI Gene:
7133
Purity:
>95% by SDS-PAGE and analyzed by silver stain.
Target:
TNF RII
References
1. Zuckerman, KS. et al. (1998) Cancer Res. 58:2217
2. Schall, TJ. et al. (1990) Cell 61:361
3. Tartaglia, LA. et al. (1992) Immunol. Today 13:151
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