Recombinant Human CD23 (Soluble)
Code | Size | Price |
---|
LEI-C1318-20ug | 20 ug | £491.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Long Description:
CD23 (cluster of differentiation 23), also known as Fc epsilon RII or FcεRII, is a type 2 transmembrane C-type lectin and a member of the Ig family that is expressed on most mature B cells. CD23 is a surface marker of activated B cells as well as a low-affinity Fc receptor for IgE.1 CD23 has pleiotropic roles in the control of lymphocyte behaviour, suggesting that CD23 may interact with another ligand in addition to IgE.2 CD23 is important in the differentiation of chronic lymphocytic leukemia (CLL) from other lymphoid leukemias.3
NCBI Gene:
2208
Purity:
>95% by SDS-PAGE and HPLC
Target:
CD23
References
1. Sakai, H. et al. (1992) Nephron 60: 4042. Jean-Yves et al. (1992) Nature 358: 5053. Keating, M. et al. (2002) Cancer 94: 172
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