Anti-Human TIRP (CT-1)
| Code | Size | Price |
|---|
| LEI-T361-20ug | 20 ug | £199.00 |
Quantity:
| LEI-T361-0.1mg | 0.1 mg | £591.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ambient
Storage:
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Further Information
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Formulation:
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Immunogen:
PN:T366
Long Description:
TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-?B (5). Expression of TIRP appears to be essential for TLR4 signalling (6).
Target:
TIRP
References
1. Bowie, AG. et al. (2003) Trends in Imm. 24:286-9.2. Fenton, MJ. et al. (2003) Mol. Interv. 3:466-77.3. Akira, S. et al. (2003) Annu.Rev. Immunol. 21:335-76.4. Janeway Jr., CA. and Medzhitov, R. (2002) Annu. Rev. Immunol. 20:197-216.5. Shu, HB. et al. (2003) J. Biol. Chem.278:24526-24532.6. Barnes, BJ. et al. (2003) J. Exp. Med. 198:1043-1055.
Related Products
| Product Name | Product Code | Supplier | Anti-Human TIRP (CT-2) | LEI-T360 | Leinco Technologies | Summary Details | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TIRP (CT-2) Blocking Peptide | LEI-T365 | Leinco Technologies | Summary Details | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| TIRP (CT-1) Blocking Peptide | LEI-T366 | Leinco Technologies | Summary Details | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||