Recombinant Human MMP-2
| Code | Size | Price |
|---|
| LEI-M1251-10ug | 10 ug | £625.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Format:
The protein was 0.2 um filtered and lyophilized from a solution of 25 mM Mes, 10 mM CaCl2, 150 mM NaCl, 0.05% Brij-35, pH 5.5.
Formulation:
The protein was 0.2 um filtered and lyophilized from a solution of 25 mM Mes, 10 mM CaCl2, 150 mM NaCl, 0.05% Brij-35, pH 5.5.
Long Description:
Matrix metallopeptidase 2, also known as MMP2, is an enzyme involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP-2 degrades type IV collagen, the major structural component of basement membranes and plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. MMP2 has been found to be associated with tumor invasion in various cancers.1
NCBI Gene:
43137
Purity:
>90% by SDS-PAGE and analyzed by silver stain.
Target:
MMP-2
References
1. Viswanadha, VP. et al. (2017) J Cell Biochem. 118(9):2865-2876.
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