Leinco Technologies

Recombinant Human Erythropoietin Receptor

Product Code:
 
LEI-E225
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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LEI-E225-50ug50 ug£694.00
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Further Information

Format:
This recombinant protein was 0.2 um filtered and lyophilized from PBS with 0.1 mM EDTA and 0.05 % CHAPS, pH 7.2.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from PBS with 0.1 mM EDTA and 0.05 % CHAPS, pH 7.2.
Long Description:
The erythropoietin receptor is a transmembrane protein belonging to the member of the cytokine receptor family. The receptor is tyrosine phosphorylated upon binding by erythropoietin and associates with and activates the tyrosine kinase, JAK2, which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. EPO-R transmits signals important for both proliferation and differentiation along the erythroid lineage.1 Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.
NCBI Gene:
2057
Purity:
>90% by SDS-PAGE and analyzed by silver stain.
Target:
Erythropoietin Receptor

References

1. Siren, AL. et al. (2001) Proc Natl Acad Sci USA 98: 4044 2. Haroon, ZA. et al. (2003) Am J Pathol 163: 993