Anti-Human CD119 (IFN-γ Rα Chain)
| Code | Size | Price |
|---|
| LEI-I-600-25ug | 25 ug | £375.00 |
Quantity:
| LEI-I-600-100ug | 100 ug | £648.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Neutralisation
- Western Blot (WB)
Shipping:
Ambient
Storage:
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Further Information
Antigen Distribution:
The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
Conjugate/Tag/Label:
Antigen Affinity Purified
Immunogen:
NS0-Derived Mouse IFN-γ R1 Extracellular Domain
Long Description:
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and β chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
NCBI Gene:
15979
Target:
IFNγ Rα
References
1. Calderon, J. et al. (1988) PNAS 85:4837
2. Garcia-Sastre, A. et al. (2002) Int. Rev. Immunol. 21:305
3. Fish, E. et al. (2002) J. Interferon Cytokine Res. 22:835
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