Anti-Human GDF-15
| Code | Size | Price |
|---|
| LEI-G667-25ug | 25 ug | £398.00 |
Quantity:
| LEI-G667-100ug | 100 ug | £694.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ambient
Storage:
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Further Information
Conjugate/Tag/Label:
Antigen Affinity Purified
Format:
This antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Formulation:
This antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Immunogen:
CHO Cell-Derived Recombinant Human GDF-15
Long Description:
Growth differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes.1 GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB.2 GDF15 is predominantly expressed in the liver, with lower levels seen in some other tissues. Its expression in the liver is significantly up-regulated during injury of organs such as liver, kidney, heart and lung.1,2,3 GDF-15 is a promising new biomarker in idiopathic pulmonary arterial hypertension.4
NCBI Gene:
9518
Target:
GDF-15
References
1. Koniaris, L.et al. (2005)Shock 23: 543
2. Lee, S. et al. (2000)Mol Cell Biol 20: 3742
3. Sadoshima, J. et al. (2006)Circ Res 98 : 294
4. Wollert, KC. et al. (2008)Am J Respir Crit Cre Med. 178 : 534
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