Anti-Human IL-4 R alpha
| Code | Size | Price |
|---|
| LEI-I-638-25ug | 25 ug | £420.00 |
Quantity:
| LEI-I-638-100ug | 100 ug | £671.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: 25463
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Immunocytochemistry (ICC)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Mass Cytometry (CyTOF)
- Neutralisation
- Western Blot (WB)
Shipping:
Ambient
Storage:
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Further Information
Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Formulation:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen:
Purified Recombinant Human IL-4 R (Accession # P24394)
Long Description:
Interleukin 4 receptor (IL-4R) is a type I cytokine receptor that is expressed by lymphocytes and is well known for its role in immunomodulatory signaling and has also been documented on oligodendrocytes, suggesting involvement in glial cell interactions. IL-4R exerts a negative regulatory role on oligodendrocytes that when deleted results in enhanced myelin repair.1 IL-4R in brain tumors may serve as an attractive target for anticancer therapy.2
Target:
IL-4 R alpha
References
1. Raine, CS. et al. (2008) Am J Pathol. 173(1):119-29. 2. Puri, RK. et al. (2001) Cancer Res. 61: 8058 3. Jiang, H. et al. (2000) J. Allergy Clin. Immunol. 105:1063 4. Hall, IP. et al. (2000) Respir. Res. 1:6 5. Nelms, K. et al. (1999) Annu. Rev. Immunol. 17:701
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