Anti-Human PDGF Rβ (Clone 61520)
| Code | Size | Price |
|---|
| LEI-P278-25ug | 25 ug | £375.00 |
Quantity:
| LEI-P278-500ug | 500 ug | £773.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 61520
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ambient
Storage:
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Further Information
Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Formulation:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen:
Purified Recombinant Human PDGF Rβ (Accession # P09619)
Long Description:
Platelet-derived growth factor receptor-β (PDGFRβ) is a well-characterized plasma membrane receptor with endogeneous tyrosine kinase activity, which is autophosphorylated in response to binding of dimeric platelet-derived growth factor (PDGF) ligand.1 PDGFRβ mediates signaling important for the proliferation, migration, and survival of mesenchymal cells.2 PDGFRβ is found in all cell types 3 and is activated in breast carcinoma cells and indicate a possible role of the receptor in breast cancerogenesis.4
Target:
PDGF R beta
References
1. Gilliland, DG. et al. (1996) Proc Natl Acad Sci USA 93: 14845
2. Ronnstrand, L. et al. (1998) Biochim Biophys Acta 1378: F79
3. Fischer, B. et al. (1997) Acta Anatomica 159: 194
4. Valius, M. et al. (2005) Biologija 1: 61
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