Anti-Rat Jagged-1 (Clone 72017)
| Code | Size | Price |
|---|
| LEI-J108-25ug | 25 ug | £375.00 |
Quantity:
| LEI-J108-500ug | 500 ug | £773.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 72017
Regulatory Status: RUO
Target Species: Rat
Application: Western Blot (WB)
Shipping:
Ambient
Storage:
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Further Information
Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Formulation:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen:
NS0-Derived Recombinant Rat Jagged 1 Extracellular Domain
Long Description:
Jagged 1 (JAG1) is a cell surface protein that functions in an embryologically important signaling pathway, known as the Notch signaling pathway, which is a highly conserved cell signaling system.1 JAG1 plays an essential role in tissue formation during embryonic development of primitive organisms.2 JAG1 is a strong candidate gene for Alagille syndrome (AGS)3 which is an autosomal dominant disorder with developmental abnormalities affecting the liver, heart, eyes, vertebrae, and craniofacial region.4
NCBI Gene:
29146
Target:
Jagged-1
References
1. Spinner, NB. et al. (2001) Semin Liver Dis. 21: 525
2. Bhatia, M. et al. (2000) J Exp Med. 192: 1365
3. Chandrasekharappa, SC. et al. (1997) Genomics 43: 376
4. DeVirgilis, S. et al. (1999) Hum Mutat. 14: 394
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