Anti-Human PEDF - Biotin
| Code | Size | Price |
|---|
| LEI-S587-50ug | 50 ug | £739.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ambient
Storage:
The lyophilized biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Further Information
Conjugate/Tag/Label:
Biotin
Format:
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 50 ug of bovine serum albumin per ug of antibody with no calcium, magnesium, or preservatives present.
Formulation:
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 50 ug of bovine serum albumin per ug of antibody with no calcium, magnesium, or preservatives present.
Immunogen:
E. coli-Derived Recombinant Human Serpin F1 (aa 44 -418)
Long Description:
Pigment epithelium derived factor (PEDF) is non-inhibitory serpin with neurotrophic and anti-angiogenic functions.1 It protects immature but not mature granule cells against both natural and induced apoptosis.2 PEDF plays an important role in regulation of glial function and proliferation in the central nervous system.3 PEDF also plays important roles in the survival and maintenance of spinal motor neurons in their neuroprotection against acquired insults in postnatal life.4 It is suggested that PEDF may be of therapeutic use, especially in retinopathies where pathological neovascularization compromises vision and leads to blindness.5
NCBI Gene:
5176
Target:
PEDF
References
1. Zhang, SS. et al. (2005) J Struct Biol. 151: 130
2. Schwartz, JP. et al. (1998) J Neurosci Res. 53: 7
3. Schwartz, JP. et al. (1997) J Neurosci Res. 49: 710
4. Kuncl, RW. et al. (1999) J Neuropathol Exp Neurol. 58: 719
5. Bouck, NP. et al. (1999) Science 285: 245
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