Anti-Mouse Ephrin-B1 - Biotin
| Code | Size | Price |
|---|
| LEI-E287-50ug | 50 ug | £762.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Shipping:
Ambient
Storage:
The lyophilized biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Further Information
Conjugate/Tag/Label:
Biotin
Format:
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 50 ug of bovine serum albumin per ug of antibody with no calcium, magnesium, or preservatives present.
Formulation:
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 50 ug of bovine serum albumin per ug of antibody with no calcium, magnesium, or preservatives present.
Immunogen:
NSO-Derived Recombinant Mouse Ephrin-B1 Extracellular Domain (Accession # AAA53231)
Long Description:
Ephrin-B1 (EFNB1) is a glycoprotein that is expressed on neuroepithelial cells1 and post-synaptically on dendritic spines in the cortex, supporting a role in synaptic plasticity in this region.2 Ephrin-B1 is also highly expressed on developing peripheral nerve fibers including auditory and vestibular (statoacoustic) and dorsal root ganglion nerve fibers and provides guidance signals to these cells.3 Ephrin-B1 participates in cell-cell repulsive and attractive signaling together with its Eph receptor.4 Tyrosine phosphorylation of ephrin-B1 promotes invasion of cancer cells in vivo and is a potential therapeutic target in some types of gastrointestinal cancers.5
NCBI Gene:
13641
Target:
Ephrin-B1
References
1. Stuckmann, I. et al. (2001) J Neurosci. 21: 2726
2. Rodger, J. et al. (2009) Brian Res. 1247: 50
3. Gray, NA. et al. (2002) European J Neurosci. 16: 1499
4. Iwatsubo, T. et al. (2006) Mol Neurodegeneration 1: 2
5. Sakai, R. et al. (2007) Am J Pathol. 171: 68
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