Anti-Human MSP - Biotin
| Code | Size | Price |
|---|
| LEI-M1306-50ug | 50 ug | £716.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ambient
Storage:
The lyophilized biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Further Information
Conjugate/Tag/Label:
Biotin
Format:
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 50 ug of bovine serum albumin per ug of antibody with no calcium, magnesium, or preservatives present.
Formulation:
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 50 ug of bovine serum albumin per ug of antibody with no calcium, magnesium, or preservatives present.
Immunogen:
NSO-Derived MSP (Accession # AAA59872)
Long Description:
Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like, is serum protein with homology to hepatocyte growth factor (HGF).1 MSP is a soluble cytokine that belongs to the family of the plasminogen-related growth factors (PRGFs). PRGFs are alpha/beta heterodimers that bind to transmembrane tyrosine kinase receptors. Through binding to its receptor, MSP stimulates dissociation of epithelia and works as an inflammatory mediator by repressing the production of nitric oxide (NO).2 MSP exerts proliferative and antiapoptotic effects, suggesting that it may play a role in tubular regeneration after acute kidney injury.3
NCBI Gene:
4485
Target:
MSP
References
1. Suda, T. et al. (1997) J Clin. Invest. 9: 701
2. Paolo, M. et al. (2001) Molecular Biol. Of Cell 12: 1341
3. Camussi, G. et al. (2008) J Am Soc Nephrol. 19: 1904
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