Anti-Human MMP-1 - Biotin
| Code | Size | Price |
|---|
| LEI-M1318-50ug | 50 ug | £762.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ambient
Storage:
The lyophilized biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Further Information
Conjugate/Tag/Label:
Biotin
Format:
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 50 ug of bovine serum albumin per ug of antibody with no calcium, magnesium, or preservatives present.
Formulation:
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 containing 50 ug of bovine serum albumin per ug of antibody with no calcium, magnesium, or preservatives present.
Immunogen:
Purified Recombinant Human MMP-1 (Accession # P03956)
Long Description:
Matrix metallopeptidase 1 (interstitial collagenase), also known as MMP1 is an enzyme involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP-1 is the only enzyme able to initiate breakdown of the interstitial collagens, collagen type 1, collagen type 2, and collagen type 3.1,2 MMP-1 plays an important role in diverse physiologic processes such as development, tissue morphogenesis, and wound repair. Expression of MMP-1 is a prognostic marker for hematogenous metastasis of colorectal cancer.3
NCBI Gene:
4312
Target:
MMP-1
References
1. Brinckerhoff, CE. et al. (1987) Oncology 64: 337 2. Saffarian, S. et al. (2004) Science 306: 108 3. Sunami, E. et al. (1987) Oncologist 5: 108
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