Human TL-1A ELISA Development Kit
| Code | Size | Price |
|---|
| LEI-T516-5plates | 5 plates | £637.00 |
Quantity:
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Overview
Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Further Information
Long Description:
TNF-ligand-related molecule 1A (TL1A), is an endothelium-derived T cell costimulator and a ligand for tumor necrosis factor receptor superfamily members DR3 and decoy receptor 3.1 TL1A binds to the death-domain receptor (DR)3 and provides costimulatory signals to activated lymphocytes. Through this interaction, TL1A induces secretion of IFN-γ. Blockade of the TL1A/DR3 pathway may offer therapeutic opportunities in Crohn's disease.2
Target:
TNF-Ligand-Related Molecule 1-A
References
1. Wei P et al. (2003) J Biol Chem. 278: 39251
2. Fabio Cominelli et al. (2006) PNAS 103: 8441
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