Recombinant Human Siglec-2
| Code | Size | Price |
|---|
| LEI-S595-50ug | 50 ug | £580.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
Ambient
Storage:
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Further Information
Long Description:
Siglecs, short for sialic acid binding Ig-like lectins are cell surface receptors and members of the immunoglobulin superfamily (IgSF) that recognize sialic acids. Their ability to recognize sialic acids using an immunoglobulin domain places them in the group of I-type (Ig-type) lectins. They are transmembrane proteins that contain an N-terminal V-like immunoglobulin (IgV) domain that binds sialic acid and a variable number of C2-type Ig (IgC2) domains. The subsequent cloning of sialoadhesin by Crocker revealed homology to CD22 (Siglec-2), CD33 (Siglec-3) and myelin-associated glycoprotein (MAG/Siglec-4), leading to a proposal for a family of "sialoadhesins". Varki then suggested the term Siglec as better alternative, and as a subset of I-type (Ig-type) lectins.
NCBI Gene:
933
Purity:
>95% by SDS Page and analyzed by silver stain.
Target:
Siglec-2
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